Dying to Lose Weight

April 11, 2014– Sixty people worldwide have died trying to lose weight using the drug, DNP. During the last decade, DNP, a chemical once used to make explosives, has become popular amongst bodybuilders for aid in weight loss. It was first discovered in the early 1930s, that the chemical could aid in weight loss. However, five years after its use as a diet pill, the Food and Drug Administration withdrew DNP from the market due to its toxicity and deemed DNP an illegal drug.

Earlier this month, a study was published in The Respiratory Physiology and Neurobiology Journal and tested the effect of DNP on rats, measuring DNP affect on metabolic rates and breathing patterns. The study found that DNP diminished ventilation response, thereby affecting regular breathing patterns in rats.

Diet pills usually work by increasing our metabolic rate, however, previous studies have shown that DNP increases metabolic rate to dangerous levels, thus causing breathing difficulties, fever, dehydration, nausea, irregular heartbeats, and many other side effects.

When DNP first appeared on the market, around 100,000 people in the U.S. had taken the drug, many of whom purchased the drug without a prescription. Even today, the drug is still purchased illegally.

Sources

http://www.ncbi.nlm.nih.gov/pubmed/24703970

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1558869/?page=1

http://www.ncbi.nlm.nih.gov/pubmedhealth/behindtheheadlines/news/2014-01-15-new-warnings-issued-over-deadly-dnp-diet-drug/

http://www.theguardian.com/science/the-h-word/2014/feb/06/dnp-deadly-weight-loss-drug-science-history

http://www.jbc.org/content/173/2/807.full.pdf+html

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