{"id":1060,"date":"2021-01-10T01:50:43","date_gmt":"2021-01-10T01:50:43","guid":{"rendered":"http:\/\/blogs.dickinson.edu\/arnoldt\/?p=1060"},"modified":"2021-02-20T14:58:08","modified_gmt":"2021-02-20T14:58:08","slug":"natural-hdac-inhibitors-alter-histones-gene-expression-and-development","status":"publish","type":"post","link":"https:\/\/blogs.dickinson.edu\/arnoldt\/2021\/01\/10\/natural-hdac-inhibitors-alter-histones-gene-expression-and-development\/","title":{"rendered":"Natural HDAC inhibitors alter histones, gene expression, and development"},"content":{"rendered":"<p><a href=\"http:\/\/blogs.dickinson.edu\/arnoldt\/2020\/04\/17\/natural-hdac-inhibitors-alter-histones-gene-expression-and-development\/img_5064\/\" rel=\"attachment wp-att-1061\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-1061\" src=\"http:\/\/blogs.dickinson.edu\/arnoldt\/files\/2020\/04\/IMG_5064-225x300.jpg\" alt=\"pupae\" width=\"225\" height=\"300\" srcset=\"https:\/\/blogs.dickinson.edu\/arnoldt\/files\/2020\/04\/IMG_5064-225x300.jpg 225w, https:\/\/blogs.dickinson.edu\/arnoldt\/files\/2020\/04\/IMG_5064-768x1024.jpg 768w, https:\/\/blogs.dickinson.edu\/arnoldt\/files\/2020\/04\/IMG_5064-113x150.jpg 113w, https:\/\/blogs.dickinson.edu\/arnoldt\/files\/2020\/04\/IMG_5064-1152x1536.jpg 1152w, https:\/\/blogs.dickinson.edu\/arnoldt\/files\/2020\/04\/IMG_5064-1536x2048.jpg 1536w, https:\/\/blogs.dickinson.edu\/arnoldt\/files\/2020\/04\/IMG_5064-973x1297.jpg 973w, https:\/\/blogs.dickinson.edu\/arnoldt\/files\/2020\/04\/IMG_5064-508x677.jpg 508w, https:\/\/blogs.dickinson.edu\/arnoldt\/files\/2020\/04\/IMG_5064-scaled.jpg 1920w\" sizes=\"auto, (max-width: 225px) 100vw, 225px\" \/><\/a>Our work with HDACis from plants, microbes, and other organisms demonstrates the role of these molecules in nature.\u00a0 Here they alter development of common insects by changing patters of histone acetylation and gene expression.\u00a0 In these model organisms plant-derived HDACis have biochemical activities which may make them useful in the treatment of neurological disorders in human subjects.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Our work with HDACis from plants, microbes, and other organisms demonstrates the role of these molecules in nature.\u00a0 Here they alter development of common insects by changing patters&#8230;<\/p>\n","protected":false},"author":1263,"featured_media":1061,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1060","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/blogs.dickinson.edu\/arnoldt\/wp-json\/wp\/v2\/posts\/1060","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.dickinson.edu\/arnoldt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.dickinson.edu\/arnoldt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.dickinson.edu\/arnoldt\/wp-json\/wp\/v2\/users\/1263"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.dickinson.edu\/arnoldt\/wp-json\/wp\/v2\/comments?post=1060"}],"version-history":[{"count":0,"href":"https:\/\/blogs.dickinson.edu\/arnoldt\/wp-json\/wp\/v2\/posts\/1060\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blogs.dickinson.edu\/arnoldt\/wp-json\/wp\/v2\/media\/1061"}],"wp:attachment":[{"href":"https:\/\/blogs.dickinson.edu\/arnoldt\/wp-json\/wp\/v2\/media?parent=1060"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.dickinson.edu\/arnoldt\/wp-json\/wp\/v2\/categories?post=1060"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.dickinson.edu\/arnoldt\/wp-json\/wp\/v2\/tags?post=1060"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}